diff --git a/tools/osx/macosx_bundle.sh b/tools/osx/macosx_bundle.sh
index 44cacef88..fd3a84c14 100644
--- a/tools/osx/macosx_bundle.sh
+++ b/tools/osx/macosx_bundle.sh
@@ -137,43 +137,43 @@ rm -r "${LIB}"/gdk-pixbuf-2.0
 "${GTK_PREFIX}/bin/gtk-query-immodules-3.0" "${LIB}"/{im*.so,libprint*.so} > "${ETC}/gtk-3.0/gtk.immodules"
 sed -i "" -e "s|${PWD}/RawTherapee.app/Contents/|/Applications/RawTherapee.app/Contents/|" "${ETC}/gtk-3.0/gdk-pixbuf.loaders" "${ETC}/gtk-3.0/gtk.immodules"
 
-ditto {"${GTK_PREFIX}","${RESOURCES}"}/share/glib-2.0/schemas
-"${GTK_PREFIX}/bin/glib-compile-schemas" "${RESOURCES}/share/glib-2.0/schemas"
+ditto {"/usr/local","${RESOURCES}"}/share/glib-2.0/schemas
+"/usr/local/bin/glib-compile-schemas" "${RESOURCES}/share/glib-2.0/schemas"
 
 msg "Copying shared files from ${GTK_PREFIX}:"
-ditto {"${GTK_PREFIX}","${RESOURCES}"}/share/mime
+ditto {"/usr/local","${RESOURCES}"}/share/mime
 # GTK3 themes
-ditto {"${GTK_PREFIX}","${RESOURCES}"}/share/themes/Mac/gtk-3.0/gtk-keys.css
-ditto {"${GTK_PREFIX}","${RESOURCES}"}/share/themes/Default/gtk-3.0/gtk-keys.css
+ditto {"/usr/local","${RESOURCES}"}/share/themes/Mac/gtk-3.0/gtk-keys.css
+ditto {"/usr/local","${RESOURCES}"}/share/themes/Default/gtk-3.0/gtk-keys.css
 # Adwaita icons
 iconfolders=("16x16/actions" "16x16/devices" "16x16/mimetypes" "16x16/places" "16x16/status" "48x48/devices")
 for f in "${iconfolders[@]}"; do
-    ditto {"${GTK_PREFIX}","${RESOURCES}"}/share/icons/Adwaita/"$f"
+    ditto {"/usr/local","${RESOURCES}"}/share/icons/Adwaita/"$f"
 done
-ditto {"${GTK_PREFIX}","${RESOURCES}"}/share/icons/Adwaita/index.theme
-"${GTK_PREFIX}/bin/gtk-update-icon-cache-3.0" "${RESOURCES}/share/icons/Adwaita"
+ditto {"/usr/local","${RESOURCES}"}/share/icons/Adwaita/index.theme
+"/usr/local/bin/gtk-update-icon-cache" "${RESOURCES}/share/icons/Adwaita"
 
 # Copy libjpeg-turbo into the app bundle
-cp /opt/local/lib/libjpeg.62.dylib "${RESOURCES}/../Frameworks"
+cp /usr/local/lib/libjpeg.*.dylib "${RESOURCES}/../Frameworks"
 
-# Copy libexpat into the app bundle
-cp /opt/local/lib/libexpat.1.dylib "${RESOURCES}/../Frameworks"
+# Copy libexpat into the app bundle (which is keg-only)
+cp /usr/local/Cellar/expat/*/lib/libexpat.1.dylib "${RESOURCES}/../Frameworks"
 
 # Copy libz into the app bundle
-cp /opt/local/lib/libz.1.dylib "${RESOURCES}/../Frameworks"
+cp /usr/lib/libz.1.dylib "${RESOURCES}/../Frameworks"
 
 # Copy libtiff into the app bundle
-cp /opt/local/lib/libtiff.5.dylib "${RESOURCES}/../Frameworks"
+cp /usr/local/lib/libtiff.5.dylib "${RESOURCES}/../Frameworks"
 
 # Copy the Lensfun database into the app bundle
 mkdir -p "${RESOURCES}/share/lensfun"
-cp /opt/local/share/lensfun/version_2/* "${RESOURCES}/share/lensfun"
+cp /usr/local/share/lensfun/version_2/* "${RESOURCES}/share/lensfun"
 
 # Copy liblensfun to Frameworks
-cp /opt/local/lib/liblensfun.2.dylib "${RESOURCES}/../Frameworks"
+cp /usr/local/lib/liblensfun.2.dylib "${RESOURCES}/../Frameworks"
 
 # Copy libomp to Frameworks
-cp /opt/local/lib/libomp.dylib "${RESOURCES}/../Frameworks"
+cp /usr/local/lib/libomp.dylib "${RESOURCES}/../Frameworks"
 
 # Install names
 find -E "${CONTENTS}" -type f -regex '.*/(rawtherapee-cli|rawtherapee|.*\.(dylib|so))' | while read -r x; do